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Trusted to do 100,000+ tests and consultations per month.
Trusted to do 100,000+ tests and consultations per month.
PGX Medication Response DNA Test

 

PGX MEDICATION RESPONSE DNA TEST

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based on 5,700+ reviews
£399.00
£399.00 - £399.00
£399.00
£399.00 - £399.00
39 BIOMARKERS
10-15 DAYS
INSTRUCTIONS
FAQ

Discover how your DNA influences your response to many prescribed and over-the-counter medications.

Simple and accurate blood test from a laboratory you can speak to.



STEP 1 - CHOOSE YOUR SAMPLE COLLECTION OPTION
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OVERVIEW

This non-invasive pain-free swab carried out at home allows you to discover how your DNA influences your response to many prescribed and over-the-counter medications.

A simple swab of your DNA is sufficient to analyse specific genes in your DNA responsible for drug metabolism, providing assistance in choosing, or changing to, more appropriate medications at dosages suited to you, and which to avoid.  

More specifically, this PGx tests looks at  >180 single nucleotide polymorphisms (SNPs) and other genetic variants in genes that affect how your body:

  • Breaks down medications (metabolism)
  • Transports drugs around the body
  • Responds to drugs at their target
  • Is at risk for side effects

These genetic differences can help predict whether a medication is likely to:

  • Work as expected
  • Be broken down too quickly or too slowly
  • Require a higher or lower dose
  • Increase the risk of adverse effects

SHARE YOUR HEALTH STORY

Video preview
Video preview
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PHARMACOGENOMICS (PGX) MEDICATION RESPONSE  DNA TEST

This simple, pain-free swab can be done in the comfort of your own home and reveals how your DNA influences your response to a wide range of prescribed and over-the-counter medications.

Just a single swab is all that's needed to analyse the specific genes responsible for how your body metabolises drugs. The results can help guide decisions around which medications may suit you best, whether a dosage adjustment is needed, or whether a different medication might be more appropriate - as well as highlighting any medications you may want to avoid.

39 BIOMARKERS

  • 39 Genes reported on


  1. TURNAROUND TIME

    We are extremely fast, with some results available within hours and others within a working day or less, from the time your sample is in our lab. However, this is not a guarantee and should not be taken as such. This is the guideline turnaround time that can be shorter or longer.


    THIS IS NOT A GUARANTEED TURNAROUND TIME.


    We are extremely proud of our very short turnaround times and a very efficient laboratory processes, you will start receiving results as soon as they are available and have completed clinical validation.


    Whilst we accommodate the shortest of time scales, with some results available within hours, for this particular test the usual turnaround time is: 10-15 Days.

  1. WILL I HAVE A GENERAL EXPLANATION OF MY RESULTS?

    Yes, our doctors put a huge amount of effort into your online Health Dashboard, which will have explanations of what each biomarker is, the normal reference ranges and what it means if you are outside of them.


    This service is included in the price of all our tests.

  1. CAN I SEE A GP TO DISCUSS MY RESULTS?

    Yes, usually the same or next day.


    One Day Tests has a fantastic clinical team of consultants and GPs. Once you have your results you can book an online video consultation to discuss your results.


    Our clinical team consists of practicing NHS and private GPs, who work closely with our laboratory and can tell you what your test results mean for you. Having an integrated laboratory and GP services makes your health journey seamless and extremely efficient.


    This service is not included in the price of the test, it is charged separately, should you wish to book it.

DOCTOR'S COMMENTS

Hi, I am Dr. Adam Staten and here's my view on this test as a GP and Clinical Director at One Day Tests.

DR. ADAM STATEN - GP VIEW AND RED FLAG SYMPTOMS

Red flag symptoms for the PGX Medication Response DNA Test

Your Results and Health Dashboard

The results of your PGX Medication Response DNA Test will be emailed to you as a secured PDF file, ready for your GP and will also be uploaded to our Health Dashboard area of the website. It’s a unique and powerful tool, powered by our in-house clinical analysis research, to match your biomarkers across test panels and symptoms, as well as provide clinical commentary on all individual biomarkers you tested for. 

The health dashboard will also provide "panel level" commentary - a birds eye view of the biomarkers that were tested. This feature allows you to view your test results and clinical commentary, and compare them to previous results, giving you a clear understanding of how your health is progressing.

By using the Health Dashboard, you can identify changes in your biomarkers and make necessary adjustments to your lifestyle. This added value is immense, as it empowers you to monitor your health and make informed decisions about your well-being.

It's free and is available with all of our tests.

SAVE WITH SUBSCRIPTION PLANS AND MEMBERSHIPS

The best way to look after your health is to do so regularly. This is easy to do with our continual monitoring plans which give you a discount on future tests. You choose the frequency and we'll do the rest.

  • Subscriptions to the same test. This can be done on this page, just choose a testing plan above.
  • Membership plans - Flex, Performance and Longevity.

When you purchase a subscription, we will deliver your home test kits or allow you to book appointments in line with your chosen frequency. 

You will be able to track your biomarkers over time in our powerful Health Dashboard, where results will be automatically updated for you. 

There are no minimum purchases with our membership plans, but there is a minimum of 3 tests with any subscription for a specific test, after which you can pause/restart/cancel at any time.

SPECIAL INSTRUCTIONS

Hi, I am Stefania Brown, I am the Laboratory Manager at One Day Tests and here are the lab's special requests for the PGX Medication Response DNA Test.

SPECIAL INSTRUCTIONS

No special instructions

Home test kit - how it works with the PGX Medication Response DNA Test

Our DNA test kits are simple and convenient.

The most important step in doing a blood test at home is to read the instructions very carefully. The process is very simple, but there are a few pitfalls you need to be aware of - you will save yourself a lot of time if you do it right the first time around!

  • Full printed instructions will arrive with your kit - please read them carefully.
  • Do not eat, drink, smoke, chew gum, use mouthwash or brush your teeth at least 30 minutes before swabbing your cheek.
  • Package the sample in the same box the kit came in. Otherwise, Royal Mail or DPD will reject it. The sample tubes go into a pouch, then into a cardboard box, and then into a return envelope. All of this is provided in the kit: please use it.

We look forward to receiving your sample in our lab!

WHY CHOOSE US?

Hello! My name is Dr. Vinesh Mistry, I am part of the GP team here at One Day Tests and here is why you should trust us with your testing.

QUICK AND ACCURATE RESULTS DIRECT FROM A LABORATORY.

We run our own regulated laboratories and our own accredited clinics. We manufacture our own approved home sample collection kits. Your results are looked after by our fantastic clinical governance team and our super-talented biomedical science team.

When you book your test with us - you book directly with the lab. This means accuracy and responsible duty of care, direct access to the provider and extremely fast turnaround times.

Finally, our customer services rock! You can ask the lab a question any time or you can speak to a real human. You can email us on [email protected] or give us a call on 0127 309 2844.

FREQUENTLY ASKED QUESTIONS

Hi, I am Lana Nela, Lead Nurse, and here is what we are frequently asked about this test.

FREQUENTLY ASKED QUESTIONS

Here are some of the most frequently asked questions about the PGX Medication Response DNA Test.

What are the benefits of a Pharmacogenomics test? 

Pharmacogenomics testing has revealed that more than 7 out of 10 of us are not “normal” metabolisers (the rate at which we break down a substance or medicine in our body) of many commonly prescribed medications covering multiple conditions. This results in a drug being ineffective or resulting in a higher side effect profile in many of us. By identifying how our DNA influences our response to our medications we can reduce the number of side effects we might be experiencing. You may be able to reduce the length of time you are on a drug, as well as improve overall quality of life by starting more effective treatments.

The test is particularly beneficial if you are on five or more medications as you are at a higher risk of experiencing side effects related to drug–drug/drug–gene interactions. These side effects include; weight gain, cardiovascular complications (such as bleeding, bruising, anaemia, fatigue, bradycardia, coughs), sedation, sexual dysfunction, gastrointestinal issues, nephrotoxicity, hormonal imbalances, antimicrobial resistance, nausea and dizziness.

Genetic differences can help predict whether a medication is likely to:

  • Work as expected
  • Be broken down too quickly or too slowly
  • Require a higher or lower dose
  • Increase the risk of adverse effects

How accurate is this test?

The results meet stringent quality control metrics for DNA isolation and genotyping. SNPs are processed in an OpenArray platform. Each call has an estimated quality value >95%, based on the autocaller algorithm in the TaqMan® Genotyper software (ThermoFisher Scientific). Copy number calls are accepted when confidence values are >95%. The HLA assays are processed using an RT-PCR-based presence/absence assay, and HLA positive calls are sequenced using Sanger technology to confirm. To avoid false negatives in HLA genotyping, if the presence/absence assay results are uncertain and Sanger sequencing results do not confirm them, a positive call is made. 

The annotations and interpretations provided in the report are based on scientific literature and do not take into account drug-drug interactions, medical conditions or other clinical factors that may affect medication response. Gene-drug interactions are ranked according to guidelines, level of evidence and clinical utility. Genetic test results and interpretation may be inaccurate for individuals who have undergone or are receiving non-autologous blood transfusion, tissue, or organ transplant therapies. 

Will my GP be able to use the test results? 

The results are displayed very clearly and are easy to interpret. You will be able to use these to help guide discussions with your GP as to which medication options are likely to be best for you. 

Would I need to do this test again in the future?

No. As our DNA does not change during our life this is a once off test for life. Your medical practitioner reanalyses your report as new possible medications are offered to you, with no need to retest. 

What is included in the test kits?

Our kit will include:

Easy to follow instructions for use and a consent form, plus the following items:

  • A swab
  • Protective shipping pouch
  • A form for you to complete and sign that you will need to send back along with your swab
  • Tracked 24 prepaid return postage box

WHY HAVE THE TEST?

Hi, I am Nader Eldarf, I am a Biomedical Scientist in our laboratory and here is why it's important to take this test.

  1. WHY HAVE THE PGX MEDICATION RESPONSE DNA TEST?

    This tests will:

    Give you a comprehensive clinically actionable DNA test for drug response

    Identify how you respond to a medication and your risk of unwanted side-effects

    Identify medications that you should avoid completely

    Help improve your medication prescribers’ understanding of what the best and most appropriate medication would be to manage your illness. for example, the lowest effective dose of a medicine that is the most effective for you. 

IS THIS TEST RIGHT FOR YOU?

Hi, I am Sandeep Patel, I am the Laboratory Director at One Day Tests. Here are the symptoms that you may wish to address with this test.

  1. IS THE PGX MEDICATION RESPONSE DNA TEST RIGHT FOR YOU?

    Pharmacogenomics testing has revealed that more than 7 out of 10 of us are not “normal” metabolisers (the rate at which we break down a substance in our body) of many commonly prescribed medications covering multiple conditions. This results in a drug being ineffective or resulting in significant side effects in many of us. By identifying how our DNA influences our response to our medications we can reduce the number of side effects we might be experiencing, either now, or in the future. You may be able to reduce the length of time you are on a drug, as well as improve overall quality of life by starting more effective treatments.



    The test is particularly beneficial if you are on five or more medications as you are at a higher risk of experiencing side effects related to drug–drug/drug–gene interactions. These side effects include; weight gain, cardiovascular complications (such as bleeding, bruising, anaemia, fatigue, bradycardia, coughs), sedation, sexual dysfunction, gastrointestinal issues, nephrotoxicity, hormonal imbalances, antimicrobial resistance, nausea and dizziness.

  1. SYMPTOMS AND TAGS

    Erectile disfunction and Lack of libido