Skip to content
Trusted to do 100,000+ tests and consultations per month.
Trusted to do 100,000+ tests and consultations per month.
Gluten and Coeliac Screen Blood Test

 


GLUTEN AND COELIAC SCREEN BLOOD TEST

Trustpilot
£96.00
£96.00 - £96.00
£96.00
£120.00
£120.00 - £120.00
£120.00
Save 20% Save 20%
4 BIOMARKERS
14 DAYS
INSTRUCTIONS
FAQ

Coeliac disease is a lifelong autoimmune disease that is caused by a reaction to gluten. This test measures Gliadin and Transglutaminase antibodies.

Simple and accurate blood test from a laboratory you can speak to.



STEP 1 - CHOOSE YOUR SAMPLE COLLECTION OPTION
Trustpilot

GLUTEN AND COELIAC SCREEN BLOOD TEST OVERVIEW

Our coeliac screen involves measuring several immunological markers to assess your body’s response to gluten, a protein found in wheat, barley, and rye.

Total IgA is checked first to rule out IgA deficiency - a condition that can yield false-negative results on other IgA-based tests.

Tissue Transglutaminase IgA (tTG-IgA), considered highly specific for coeliac disease, detects antibodies against the enzyme that modifies gluten peptides in the small intestine.

Gliadin IgA measures the immune response to gliadin (a gluten component) and can be helpful, particularly in young children.

Gliadin IgG can aid diagnosis in people with IgA deficiency or other immune complications.

SHARE YOUR HEALTH STORY

Video preview
Video preview
Video preview
Video preview

GLUTEN AND COELIAC SCREEN BLOOD TEST

This is a complex investigation that checks the necessary biomarkers for coeliac disease and body's reaction to gluten.

Total IgA - Total IgA quantifies overall Immunoglobulin A production in the body. In the context of coeliac screening, measuring Total IgA helps identify IgA deficiency, a condition in which the body either produces insufficient amounts of IgA or none at all. If you have an IgA deficiency, IgA-based coeliac tests may give falsely negative results, so this biomarker serves as an essential first step in accurate diagnostic evaluation.

Tissue Transglutaminase IgA (tTG-IgA) - Tissue Transglutaminase IgA is the primary and most specific serological marker for diagnosing coeliac disease. When people with coeliac disease consume gluten, their immune system produces antibodies against tissue transglutaminase, an enzyme involved in the post-translational modification of gluten peptides. Elevated tTG-IgA levels strongly indicate an immune-mediated reaction consistent with coeliac pathology, making it a cornerstone of diagnostic testing.

Gliadin IgA - Gliadin is one of the main protein components of gluten. Gliadin IgA antibodies are another measure of the immune system’s reaction to ingested gluten. Though Gliadin IgA can be useful, particularly in evaluating younger children, it is generally considered less specific than tTG-IgA for coeliac disease. Nonetheless, it can provide additional clinical insights when combined with other biomarkers.

Gliadin IgG - Gliadin IgG testing is often used alongside or as an alternative to Gliadin IgA in people who have confirmed or suspected IgA deficiency. In such cases, IgA-based tests may not be accurate, so testing for IgG antibodies against gliadin can help detect an ongoing immune response to gluten. Elevated Gliadin IgG levels may warrant further diagnostic steps for coeliac disease or other gluten-related disorders.

4 BIOMARKERS

  1. GLUTEN AND COELIAC SCREENS

    - Total IgA
    - Tissue Transglutaminase IgA
    - Gliadin IgA
    - Gliadin IgG

  2. UPGRADE

    Need more biomarkers? Add this test to our Essential All Systems Blood Test.

  1. TURNAROUND TIME

    We are extremely fast, with some results available within hours and others within a working day or less, from the time your sample is in our lab. However, this is not a guarantee and should not be taken as such. This is the guideline turnaround time that can be shorter or longer.


    THIS IS NOT A GUARANTEED TURNAROUND TIME.


    We are extremely proud of our very short turnaround times and a very efficient laboratory processes, you will start receiving results as soon as they are available and have completed clinical validation.


    Whilst we accommodate the shortest of time scales, with some results available within hours, for this particular test the usual turnaround time is: 14 working days.

  1. WILL I HAVE A GENERAL EXPLANATION OF MY RESULTS?

    Yes, our doctors put a huge amount of effort into your online Health Dashboard, which will have explanations of what each biomarker is, the normal reference ranges and what it means if you are outside of them.


    This service is included in the price of all our tests.

  1. CAN I SEE A GP TO DISCUSS MY RESULTS?

    Yes, usually the same or next day.


    One Day Tests has a fantastic clinical team of consultants and GPs. Once you have your results you can book an online video consultation to discuss your results.


    Our clinical team consists of practicing NHS and private GPs, who work closely with our laboratory and can tell you what your blood test results mean for you. Having an integrated laboratory and GP services makes your health journey seamless and extremely efficient.


    This service is not included in the price of the test, it is charged separately, should you wish to book it.

DOCTOR'S COMMENTS

Hi, I am Dr. Adam Staten and here's my view on this test as a GP and Clinical Director at One Day Tests.

DR. ADAM STATEN - GP VIEW AND RED FLAG SYMPTOMS

Coeliac and gluten investigations are not always straightforward.

You may need clinical interpretation, which takes into account not only the numeric values of the tests but also the patient’s medical history, symptoms, dietary habits, and any relevant comorbidities. Certain factors, such as selective IgA deficiency, recent dietary changes, or coinciding autoimmune disorders, can influence laboratory readings, necessitating professional judgement.

Once you receive your results you may benefit from a conversation with one of our GPs.

Red flag symptoms for the Gluten and Coeliac Screen Blood Test

Please get in touch with your doctor if you are experiencing any persistent or worrying abdominal symptoms.

Your Results and Health Dashboard

The results of your Gluten and Coeliac Screen Blood Test will be emailed to you as a secured PDF file, ready for your GP and will also be uploaded to our Health Dashboard area of the website. It’s a unique and powerful tool, powered by our in-house clinical analysis research, to match your biomarkers across test panels and symptoms, as well as provide clinical commentary on all individual biomarkers you tested for.

The health dashboard will also provide "panel level" commentary - a birds eye view of the biomarkers that were tested. This feature allows you to view your test results and clinical commentary, and compare them to previous results, giving you a clear understanding of how your health is progressing.

By using the Health Dashboard, you can identify changes in your biomarkers and make necessary adjustments to your lifestyle. This added value is immense, as it empowers you to monitor your health and make informed decisions about your well-being.

It's free and is available with all of our tests.

SAVE ON CONTINUOUS MONITORING WITH OUR SUBSCRIPTION PLAN

The best way to look after your health is to do so regularly. This is easy to do with our continual monitoring plans which give you a discount on future blood tests. You choose the frequency and we'll do the rest.

When you purchase a subscription, we will deliver your home test kits or allow you to book appointments in line with your chosen frequency. You will be able to track your biomarkers over time in our powerful Health Dashboard, where results will be automatically updated for you. There is a minimum of 3 tests with any subscription, after which you can pause/restart/cancel at any time.

SPECIAL INSTRUCTIONS

Hi, I am Stefania Brown, I am the Laboratory Manager at One Day Tests and here are the lab's special requests for the Gluten and Coeliac Screen Blood Test.

SPECIAL INSTRUCTIONS

NICE (medical regulatory and guidelines body) recommends including gluten in more than one meal a day for at least six weeks before testing.

Whilst we don't recommend any specific amount of gluten, some must be present for the testing to be accurate and the reaction levels measurable.

Clinic appointment - how to prepare for the Gluten and Coeliac Screen Blood Test

If you are coming into one of our clinics for the test, this is what you need to do before you arrive:

  • Read the instructions in the SPECIAL INSTRUCTIONS section
  • Drink plenty of water about an hour before the appointment.
  • Avoid coffee/tea/energy drinks. Water is good!
  • That’s it! We’ll do the rest.

We look forward to receiving your sample in our lab!

WHY CHOOSE US?

Hello! My name is Dr. Vinesh Mistry, I am part of the GP team here at One Day Tests and here is why you should trust us to test your blood.

QUICK AND ACCURATE RESULTS DIRECT FROM A LABORATORY.

We run our own regulated laboratories and our own accredited clinics. We manufacture our own approved home sample collection kits. Your results are looked after by our fantastic clinical governance team and our super-talented biomedical science team.

When you book your test with us - you book directly with the lab. This means accuracy and responsible duty of care, direct access to the provider and extremely fast turnaround times.

Finally, our customer services rock! You can ask the lab a question any time or you can speak to a real human. You can email us on hello@onedaytests.com or give us a call on 0127 309 2844.

FREQUENTLY ASKED QUESTIONS

Hi, I am Lana Nela, Lead Nurse, and here is what we are frequently asked about this test.

FREQUENTLY ASKED QUESTIONS

Here are some of the most frequently asked questions about the Gluten and Coeliac Screen Blood Test.

Why measure Total IgA?

Measuring total Immunoglobulin A (IgA) is critical in coeliac disease screening to rule out selective IgA deficiency, a condition wherein individuals produce little to no IgA.

If someone has IgA deficiency, tests that rely on IgA antibodies (such as tissue transglutaminase IgA in our panel) may yield falsely negative results, potentially leading to a missed or delayed diagnosis.

WHY HAVE THE TEST?

Hi, I am Nader Eldarf, I am a Biomedical Scientist in our laboratory and here is why it's important to take this test.

  1. WHY HAVE THE GLUTEN AND COELIAC SCREEN BLOOD TEST?

    It is important to undergo a gluten and coeliac screen because coeliac disease, if left undiagnosed or untreated, can lead to serious health consequences including malabsorption of nutrients, anaemia, bone density loss, and an increased risk of other autoimmune conditions.

IS THIS TEST RIGHT FOR YOU?

Hi, I am Sandeep Patel, I am the Laboratory Director at One Day Tests. Here are the symptoms that you may wish to address with this test.

  1. IS THE GLUTEN AND COELIAC SCREEN BLOOD TEST RIGHT FOR YOU?

    If you are experiencing symptoms such as chronic diarrhoea, persistent abdominal pain, bloating, weight loss, or unexplained nutrient deficiencies - you may benefit from a gluten and coeliac screen.

    If you have a family history of coeliac disease or autoimmune disorders - you are also at higher risk.

    If you suspect your body may be reacting to gluten or if you’ve been advised by your doctor to investigate possible coeliac disease, this screen will identify underlying immune responses to gluten.

    This will allow you to make informed decisions regarding dietary and treatment options, which can significantly improve quality of life.

  1. SYMPTOMS AND TAGS

    Coeliac and Gluten

WHY ARE BLOOD TESTS IMPORTANT?

Health monitoring is very important, you are in charge of your health - look after it.