About the test
Apolipoprotein B (apoB) is another important biomarker related to lipoproteins, but unlike apolipoprotein A1 (apoA1), it is associated with low-density lipoprotein (LDL) particles, commonly known as "bad cholesterol." LDL particles transport cholesterol from the liver to peripheral tissues, and elevated levels of LDL cholesterol in the blood are considered a significant risk factor for atherosclerosis and cardiovascular disease.
Apolipoprotein B is the primary structural protein of LDL particles, constituting about 90% of their protein content. Each LDL particle typically contains one molecule of apoB. The measurement of apoB levels in the blood can provide valuable information about the number of LDL particles present, as every LDL particle contains one apoB molecule.
LDL cholesterol is known to contribute to the formation of atherosclerotic plaques in the arteries, leading to narrowing and hardening of the blood vessels. Therefore, measuring apoB levels can help in assessing the total number of atherogenic LDL particles and their potential impact on cardiovascular health.